Protein name:
Xanthine dehydrogenase/oxidase ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homodimer. Interacts with BTN1A1.
Function:
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species.
Subcellular Location:
Peroxisome
Cytoplasm
Secreted
Protein Attributes:
50:
MTADELVFFV | NGKKVVEKNA | DPETTLLVYL | RRKLGLCGTK | LGCGEGGCGA |
100:
CTVMISKYDR | LQNKIVHFSV | NACLAPICSL | HHVAVTTVEG | IGNTQKLHPV |
150:
QERIARSHGS | QCGFCTPGIV | MSMYTLLRNQ | PEPTVEEIEN | AFQGNLCRCT |
200:
GYRPILQGFR | TFAKDGGCCG | GSGNNPNCCM | NQTKDQTVSL | SPSLFNPEDF |
250:
KPLDPTQEPI | FPPELLRLKD | TPQKKLRFEG | ERVTWIQAST | MEELLDLKAQ |
300:
HPDAKLVVGN | TEIGIEMKFK | NMLFPLIVCP | AWIPELNSVV | HGPEGISFGA |
350:
SCPLSLVESV | LAEEIAKLPE | QKTEVFRGVM | EQLRWFAGKQ | VKSVASIGGN |
400:
IITASPISDL | NPVFMASGAK | LTLVSRGTRR | TVRMDHTFFP | GYRKTLLRPE |
450:
EILLSIEIPY | SKEGEFFSAF | KQASRREDDI | AKVTSGMRVL | FKPGTIEVQE |
500:
LSLCFGGMAD | RTISALKTTP | KQLSKSWNEE | LLQSVCAGLA | EELQLAPDAP |
550:
GGMVEFRRTL | TLSFFFKFYL | TVLQKLGRAD | LEDMCGKLDP | TFASATLLFQ |
600:
KDPPANVQLF | QEVPKDQSEE | DMVGRPLPHL | AANMQASGEA | VYCDDIPRYE |
650:
NELSLRLVTS | TRAHAKITSI | DTSEAKKVPG | FVCFLTAEDV | PNSNATGLFN |
700:
DETVFAKDEV | TCVGHIIGAV | VADTPEHAQR | AARGVKITYE | DLPAIITIQD |
750:
AINNNSFYGS | EIKIEKGDLK | KGFSEADNVV | SGELYIGGQE | HFYLETNCTI |
800:
AVPKGEAGEM | ELFVSTQNTM | KTQSFVAKML | GVPDNRIVVR | VKRMGGGFGG |
850:
KETRSTVVST | ALALAAHKTG | RPVRCMLDRD | EDMLITGGRH | PFLAKYKVGF |
900:
MKTGTVVALE | VAHFSNGGNT | EDLSRSIMER | ALFHMDNAYK | IPNIRGTGRI |
950:
CKTNLPSNTA | FRGFGGPQGM | LIAEYWMSEV | AITCGLPAEE | VRRKNMYKEG |
1000:
DLTHFNQKLE | GFTLPRCWDE | CIASSQYLAR | KREVEKFNRE | NCWKKRGLCI |
1050:
IPTKFGISFT | LPFLNQGGAL | VHVYTDGSVL | LTHGGTEMGQ | GLHTKMVQVA |
1100:
SRALKIPTSK | IHISETSTNT | VPNTSPTAAS | ASADLNGQGV | YEACQTILKR |
1150:
LEPFKKKKPT | GPWEAWVMDA | YTSAVSLSAT | GFYKTPNLGY | SFETNSGNPF |
1200:
HYFSYGVACS | EVEIDCLTGD | HKNLRTDIVM | DVGSSLNPAI | DIGQVEGAFV |
1250:
QGLGLFTMEE | LHYSPEGSLH | TRGPSTYKIP | AFGSIPIEFR | VSLLRDCPNK |
1300:
RAIYASKAVG | EPPLFLASSI | FFAIKDAIRA | ARAQHGDNAK | QLFQLDSPAT |
1331:
PEKIRNACVD | QFTTLCVTGV | PENCKSWSVR | I
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Rat
Mouse
Chicken
ELISA Kit for Rat Xanthine dehydrogenase/oxidase
ELISA Kit for Rat Xanthine dehydrogenase/oxidase
ELISA Kit for Rat Xanthine dehydrogenase/oxidase
ELISA Kit for Rat Xanthine dehydrogenase/oxidase
ELISA Kit for Rat Xanthine dehydrogenase/oxidase
CLIA Kit for Rat Xanthine dehydrogenase/oxidase
CLIA Kit for Rat Xanthine dehydrogenase/oxidase
CLIA Kit for Rat Xanthine dehydrogenase/oxidase
CLIA Kit for Rat Xanthine dehydrogenase/oxidase
CLIA Kit for Rat Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Rat Xanthine dehydrogenase/oxidase
Protein for Rat Xanthine dehydrogenase/oxidase
Protein for Rat Xanthine dehydrogenase/oxidase
Protein for Rat Xanthine dehydrogenase/oxidase
Protein for Rat Xanthine dehydrogenase/oxidase
Protein for Rat Xanthine dehydrogenase/oxidase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;ENZYME REGULATION;PROTEOLYTIC CONVERSION;SUBUNIT
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE OF 1-55
strain :
Sprague-Dawley .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF MUTANT ALA-535/ARG-992/SER-1324 IN COMPLEX WITH FAD; URIC ACID AND IRON-SULFUR CENTERS;CATALYTIC ACTIVITY;DISULFIDE BOND;ENZYME REGULATION;MUTAGENESIS OF CYS-535; CYS-992 AND CYS-1316;COFACTOR
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.28 ANGSTROMS) OF MUTANT ALA-335/LEU-336 IN COMPLEX WITH FAD AND IRON-SULFUR CENTER;MUTAGENESIS OF 335-TRP-PHE-336;CATALYTIC ACTIVITY;FUNCTION;COFACTOR